Prep HPLC Column, RP C4, 10um, 100A. 30mm ID x 250mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C4 Butyl is a reversed-phase HPLC stationary phase manufactured using high-purity silica with traditional butyl (C4) ligand bonding and complete double endcapping. The moderate hydrophobicity of the C4 ligand makes this stationary phase an excellent choice for purification of hydrophobic and neutral compounds while providing lower retention than C18 phases and greater retention than many C8 phases. The fully endcapped surface delivers reliable chromatographic performance and reproducible purification results in large-scale preparative applications.
68004-P30-250 is a preparative HPLC column with dimensions of 30 mm ID x 250 mm length, packed with 10 µm RP C4 Butyl particles featuring a 100 Å pore size. The large internal diameter is designed for high sample loading and efficient fraction collection, while the 250 mm length provides maximum resolving power and peak capacity for demanding purification workflows. Typical flow rates are approximately 30–80 mL/min depending on system capabilities, mobile phase conditions, and sample requirements.
This column is intended for preparative HPLC purification where target compounds are isolated and collected for further research, development, formulation, or production. The extended column length is particularly beneficial when separating closely related compounds, improving purity, or optimizing large-scale purification methods. Applications include pharmaceutical research, synthetic chemistry, natural product purification, reference standard preparation, and pilot-scale manufacturing support. A specialized preparative HPLC system capable of high flow rates, large injection volumes, and fraction collection is required. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
RP C4 Butyl stationary phase
Fully double endcapped chemistry
Traditional butyl (C4) bonded phase
Designed for preparative HPLC purification
High sample loading capacity
10 µm particles for lower operating backpressure
Suitable for high flow rates
Less retention than C18 columns
Maximum resolution with 250 mm column length
Ideal for large-scale purification and process optimization
Typical Applications
Preparative HPLC purification
Small molecule isolation
Pharmaceutical research
Synthetic chemistry
Natural product purification
Reference standard preparation
Process development
Scale-up studies
Pilot-scale purification
Fraction collection
Specifications
Product Type: Preparative HPLC Column
Stationary Phase: RP C4 Butyl
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 30 mm ID x 250 mm
Length: 250 mm
Typical Flow Rate: 30–80 mL/min
Brand: Cogent
Special Order Item Information
Important Notes
Designed for purification rather than routine analytical HPLC
Used for isolation and collection of purified compounds
Offers substantially higher sample loading capacity than analytical columns
Requires a preparative HPLC system capable of high flow rates and fraction collection
Provides less retention than C18 phases and greater retention than many C8 phases
Well suited for process development, scale-up studies, and production-support purification
Special Order Item